Article
Activation of ErbB3-PI3-kinase pathway is correlated with malignant phenotypes of adenocarcinomas.
Oncogene - 6 Mar 2003
Kobayashi Michimoto, Iwamatsu Akihiro, Shinohara-Kanda Azusa, Ihara Sayoko, Fukui Yasuhisa
Abstract excerpt
Signet-ring cell carcinomas are malignant dedifferentiated carcinomas, which are frequently found in the stomach. We previously demonstrated that a 200 kDa protein is often constitutively phosphorylated on tyrosine and bound to phosphatidylinositol 3-kinase (PI3-kinase) in signet-ring cell carcin...
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