Article
Progesterone receptors mediate male aggression toward infants.
Proceedings of the National Academy of Sciences of the United States of America - 4 Mar 2003
Schneider Johanna S, Stone Marielle K, Wynne-Edwards Katherine E, Horton Teresa H, Lydon John, O'Malley Bert, Levine Jon E
Abstract excerpt
Neuroendocrine mechanisms that mediate male aggression toward infants are poorly understood. Although testosterone is known to enhance aggression in other social contexts, evidence that it modulates aggression toward infants is equivocal. We have found that male progesterone receptor knockout (PRKO) mice exhibit no infanticidal behavior and little aggression toward young. Male PRKO mice also display significantly...
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