Article
[Alteration of multiple tumor metastatic genes with correlation to metastasis in ovarian carcinoma].
Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao - 1 Jan 2002
Huang Guangqi, He Guoli, Song Yi
Abstract excerpt
OBJECTIVE: To investigate the expression and mutation of MTA1, nm23H1 and E-cadherin(E-cad) genes in ovarian carcinoma (OC) in relation to lymph node (LN) metastasis. METHODS: A panel of normal ovarian tissues, primary OC specimens and corresponding LNS was examined for mRNA expression and mutation of MTA1 and nm23H1 and protin expression of E-cad genes by using RT-PCR, RT-PCR-SSCP and immunohistochemistry....
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