Article
Unique appearance of proliferating antigen-presenting cells expressing DC-SIGN (CD209) in the decidua of early human pregnancy.
The American journal of pathology - 1 Mar 2003
Kämmerer Ulrike, Eggert Andreas O, Kapp Michaela, McLellan Alexander D, Geijtenbeek Teunis B H, Dietl Johannes, van Kooyk Yvette, Kämpgen Eckhart
Abstract excerpt
Intact human pregnancy can be regarded as an immunological paradox in that the maternal immune system accepts the allogeneic embryo without general immunosuppression. Because dendritic cell (DC) subsets could be involved in peripheral tolerance, the uterine mucosa (decidua) was investigated for DC populations. Here we describe the detailed immunohistochemical and functional characterization of HLA-DR-positive...
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