Article
Genetic and environmental factors influencing the Placental Growth Factor (PGF) variation in two populations.
PloS one - 1 Jan 2012
Sorice Rossella, Ruggiero Daniela, Nutile Teresa, Aversano Mario, Husemoen Lotte, Linneberg Allan, Bourgain Catherine, Leutenegger Anne-Louise, Ciullo Marina
Abstract excerpt
Placental Growth Factor (PGF) is a key molecule in angiogenesis. Several studies have revealed an important role of PGF primarily in pathological conditions (e.g.: ischaemia, tumour formation, cardiovascular diseases and inflammatory processes) suggesting its use as a potential therapeutic agent. However, to date, no information is available regarding the genetics of PGF variability. Furthermore, even though the...
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