Article
Overcoming resistance: virologic response to a salvage regimen with the combination of ritonavir plus indinavir.
HIV clinical trials - 1 Jan 2000
Casado Jose L, Moreno Ana, Martí-Belda Paloma, Sabido Raquel, Pinheiro Sofía, Bermudez Elena, Antela Antonio, Dronda Fernando, Perez-Elías María J, Moreno Santiago
Abstract excerpt
PURPOSE: To explore the possibility of overcoming resistance to protease inhibitors (PIs) and to determine the resistance cutoff values that continue to predict treatment failure with a dual PI regimen. METHOD: We performed a prospective study of 53 patients who had failed in several PIs and who were included in a ritonavir (RTV) plus indinavir (IDV) salvage regimen. Median HIV RNA level decrease was evaluated...
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