Article
Effect of cessation of zidovudine prophylaxis to reduce vertical transmission on maternal HIV disease progression and survival.
Journal of acquired immune deficiency syndromes (1999) - 1 Feb 2003
Bardeguez Arlene D, Shapiro David E, Mofenson Lynne M, Coombs Robert, Frenkel Lisa M, Fowler Mary Glenn, Huang Sharon, Sperling Rhoda S, Cunningham Bethann, Gandia Jorge, Maupin Robert, Zorrilla Carmen D, Jones Theodore, O'Sullivan Mary Jo
Abstract excerpt
Zidovudine prophylaxis is recommended to reduce perinatal HIV-1 transmission, but there are limited data on long-term effects on women's health. Pediatrics AIDS Clinical Trials Group (PACTG) 288 was a prospective observational study among US women randomized to zidovudine or placebo in PACTG 076 that was designed to evaluate and compare postpartum clinical, immune, and viral parameters between randomized...
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