Article
Rapid development of genotypic resistance to lamivudine when combined with zidovudine in pregnancy.
Journal of medical virology - 1 Nov 1999
Clarke J R, Braganza R, Mirza A, Stainsby C, Ait-Khaled M, Wright A, Lyall H, Parker D, McClure M O, Weber J N, Taylor G P
Abstract excerpt
The prevention of mother to child transmission of HIV-1 by zidovudine monotherapy is well known, but increasingly combination anti-retroviral therapy is prescribed during pregnancy. In this prospective study, 19 pregnant women with human immunodeficiency virus-1 (HIV-1) infection who elected to take anti-retroviral therapy during the second and third trimesters were treated with zidovudine or zidovudine plus...
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