Article
Lack of Tumors in Infants With Perinatal HIV-1 Exposure and Fetal/Neonatal Exposure to Zidovudine
1 Apr 1999
Abstract excerpt
Zidovudine (ZDV) therapy during pregnancy and to the neonate reduced perinatal HIV transmission by nearly 70% in Pediatric AIDS Clinical Trials Group (PACTG) protocol 076. ZDV has been reported as positive in several in vitro carcinogenicity screening tests. We evaluated the short-term risk for tumors in 727 children with known ZDV exposure enrolled into the PACTG 076/219 and the Women and Infants Transmission...
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