Article
The role of group B streptococci beta-hemolysin expression in newborn lung injury.
Advances in experimental medicine and biology - 1 Jan 1997
Nizet V, Gibson R L, Rubens C E
Abstract excerpt
There is a direct correlation between the level of GBS beta-hemolysin expression and the ability of GBS to injury lung epithelial cells. Electron microscopy suggest the hemolysin acts as a pore-forming cytolysin. beta-hemolysin-associated lung epithelial cell injury is inhibited by surfactant pho...
Topics
- Animals
- Animals, Newborn
- Bacterial Proteins
- Disease Models, Animal
- Genes, Bacterial
- Hemolysin Proteins
- Humans
- In Vitro Techniques
- Infant, Newborn
- Lung Injury
- Mutation
- Pneumonia, Bacterial
- Rats
- Rats, Sprague-Dawley
- Streptococcal Infections
- Streptococcus agalactiae
- Virulence
