Article
Genetic clues to the molecular basis of tobacco addiction and progress towards personalized therapy.
Trends in molecular medicine - 1 Feb 2001
Walton R, Johnstone E, Munafò M, Neville M, Griffiths S
Abstract excerpt
The molecular processes that underlie addiction are beginning to unfold. Genetically determined variations in dopaminergic neurotransmission predispose to nicotine dependence. In addition, tobacco use is likely to be governed by the rate at which smokers metabolize nicotine. Functional polymorphi...
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