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Article

The Arabidopsis GNOM ARF-GEF mediates endosomal recycling, auxin transport, and auxin-dependent plant growth.

Cell - 24 Jan 2003

Geldner Niko, Anders Nadine, Wolters Hanno, Keicher Jutta, Kornberger Wolfgang, Muller Philippe, Delbarre Alain, Ueda Takashi, Nakano Akihiko, Jürgens Gerd

Abstract excerpt

Exchange factors for ARF GTPases (ARF-GEFs) regulate vesicle trafficking in a variety of organisms. The Arabidopsis protein GNOM is a brefeldin A (BFA) sensitive ARF-GEF that is required for the proper polar localization of PIN1, a candidate transporter of the plant hormone auxin. Mutations in GNOM lead to developmental defects that resemble those caused by interfering with auxin transport. Both PIN1 localization...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12553910
DOI: 10.1016/s0092-8674(03)00003-5

Genes

PIN1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Arabidopsis GNOM ARF-GEF mediates endosomal recycling, auxin transport, and auxin-dependent plant growth.PMID 12553910Read ↗

BEX1/ARF1A1C is required for BFA-sensitive recycling of PIN auxin transporters and auxin-mediated development in Arabidopsis.Semantic proximity Read ↗

Fluorescence imaging-based screen identifies ARF GEF component of early endosomal trafficking.Semantic proximity Read ↗

An ARF-GEF acting at the Golgi and in selective endocytosis in polarized plant cells.Semantic proximity Read ↗

Role of the GNOM gene in Arabidopsis apical-basal patterning--From mutant phenotype to cellular mechanism of protein action.Semantic proximity Read ↗

AtSNX1 defines an endosome for auxin-carrier trafficking in Arabidopsis.Semantic proximity Read ↗

Coordinated Activation of ARF1 GTPases by ARF-GEF GNOM Dimers Is Essential for Vesicle Trafficking in Arabidopsis.Semantic proximity Read ↗

ADP-ribosylation factor machinery mediates endocytosis in plant cells.Semantic proximity Read ↗

The Inhibitor Endosidin 4 Targets SEC7 Domain-Type ARF GTPase Exchange Factors and Interferes with Subcellular Trafficking in Eukaryotes.Semantic proximity Read ↗

BEN3/BIG2 ARF GEF is Involved in Brefeldin A-Sensitive Trafficking at the trans-Golgi Network/Early Endosome in Arabidopsis thaliana.Semantic proximity Read ↗

The exocyst complex contributes to PIN auxin efflux carrier recycling and polar auxin transport in Arabidopsis.Semantic proximity Read ↗

Functional diversification of closely related ARF-GEFs in protein secretion and recycling.Semantic proximity Read ↗

Inducible knock-down of GNOM during root formation reveals tissue-specific response to auxin transport and its modulation of local auxin biosynthesis.Semantic proximity Read ↗

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