Article
Coordinated Activation of ARF1 GTPases by ARF-GEF GNOM Dimers Is Essential for Vesicle Trafficking in Arabidopsis.
The Plant cell - 1 Aug 2020
Brumm Sabine, Singh Manoj K, Nielsen Mads Eggert, Richter Sandra, Beckmann Hauke, Stierhof York-Dieter, Fischer Angela-Melanie, Kumaran Mande, Sundaresan Venkatesan, Jürgens Gerd
Abstract excerpt
Membrane trafficking maintains the organization of the eukaryotic cell and delivers cargo proteins to their subcellular destinations, such as sites of action or degradation. The formation of membrane vesicles requires the activation of the ADP-ribosylation factor ARF GTPase by the SEC7 domain of ARF guanine-nucleotide exchange factors (ARF-GEFs), resulting in the recruitment of coat proteins by GTP-bound ARFs. In...
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