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Article

The Inhibitor Endosidin 4 Targets SEC7 Domain-Type ARF GTPase Exchange Factors and Interferes with Subcellular Trafficking in Eukaryotes.

The Plant cell - 1 Oct 2018

Kania Urszula, Nodzyński Tomasz, Lu Qing, Hicks Glenn R, Nerinckx Wim, Mishev Kiril, Peurois François, Cherfils Jacqueline, De Rycke Riet, Grones Peter, Robert Stéphanie, Russinova Eugenia, Friml Jiří

Abstract excerpt

The trafficking of subcellular cargos in eukaryotic cells crucially depends on vesicle budding, a process mediated by ARF-GEFs (ADP-ribosylation factor guanine nucleotide exchange factors). In plants, ARF-GEFs play essential roles in endocytosis, vacuolar trafficking, recycling, secretion, and polar trafficking. Moreover, they are important for plant development, mainly through controlling the polar subcellular...

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Identifiers

PMID: 30018156
DOI: 10.1105/tpc.18.00127
PMCID: PMC6241256

Genes

ARF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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