Article
The maltase-glucoamylase gene: Common ancestry to sucrase-isomaltase with complementary starch digestion activities
23 Jan 2003
Abstract excerpt
Brush-border maltase-glucoamylase (MGA) activity serves as the final step of small intestinal digestion of linear regions of dietary starch to glucose. Brush-border sucrase-isomaltase (SI) activity is complementary, through digestion of branched starch linkages. Here we report the cloning and sequencing of human MGA gene and demonstrate its close evolutionary relationship to SI. The gene is approximately 82,000...