Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Natural Selection at the Brush-Border: Adaptations to Carbohydrate Diets in Humans and Other Mammals.

Genome biology and evolution - 28 Aug 2015

Pontremoli Chiara, Mozzi Alessandra, Forni Diego, Cagliani Rachele, Pozzoli Uberto, Menozzi Giorgia, Vertemara Jacopo, Bresolin Nereo, Clerici Mario, Sironi Manuela

Abstract excerpt

Dietary shifts can drive molecular evolution in mammals and a major transition in human history, the agricultural revolution, favored carbohydrate consumption. We investigated the evolutionary history of nine genes encoding brush-border proteins involved in carbohydrate digestion/absorption. Results indicated widespread adaptive evolution in mammals, with several branches experiencing episodic selection,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptation, Biological
Share to alpha-Glucosidases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Carbohydrate Metabolism

Share to Dietary Carbohydrates

Share to Gorilla gorilla

Share to Mammals

Share to Microvilli

Share to Pan troglodytes

Source

Open in PubMed Open full text

Identifiers

PMID: 26319403
DOI: 10.1093/gbe/evv166
PMCID: PMC4607523

Genes

MGAM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Natural Selection at the Brush-Border: Adaptations to Carbohydrate Diets in Humans and Other Mammals.PMID 26319403Read ↗

Evolutionary adaptations to dietary changes.Semantic proximity Read ↗

Recent advances in understanding the adaptive evolution of metabolic genes and traits.Semantic proximity Read ↗

The maltase-glucoamylase gene: Common ancestry to sucrase-isomaltase with complementary starch digestion activitiesSemantic proximity Read ↗

Convergent relaxation of molecular constraint in mammalian herbivores highlights the roles of liver and kidney functions in carnivorySemantic proximity Read ↗

Diversity in the glucose transporter-4 gene (SLC2A4) in humans reflects the action of natural selection along the old-world primates evolution.Semantic proximity Read ↗

Global diversity, recurrent evolution, and recent selection on amylase structural haplotypes in humansSemantic proximity Read ↗

The genomics of selection in dogs and the parallel evolution between dogs and humans.Semantic proximity Read ↗

The molecular signature of selection underlying human adaptations.Semantic proximity Read ↗

Convergent and lineage-specific genomic changes shape adaptations in sugar-consuming birdsSemantic proximity Read ↗

Genomic and physiological changes in a sexually selected and frugivorous bird radiation.Semantic proximity Read ↗

Selection shapes the landscape of functional variation in wild house mice.Semantic proximity Read ↗

Selection shapes the landscape of functional variation in wild house miceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.