Article
Ischaemic strokes and homozygosity for the alpha2 807T allele of the platelet collagen receptor in young monozygotic twins.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jan 2003
Maakaroun Abdullah, Regina Sandra, Delahousse Benedicte, Saudeau Denis, Gruel Yves
Abstract excerpt
A nucleotide 807T variant of the glycoprotein Ia gene that correlates with increased platelet surface levels of the platelet collagen receptor alpha2beta1 was recently found to be associated with an increased risk of ischaemic stroke in younger patients. We report the history of twins who developed ischaemic strokes and were shown to be homozygous for the alpha2 807T allele. The twins developed ischaemic strokes...
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