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Article

Endothelin as a regulator of cardiovascular function in health and disease

1 Aug 1998

Abstract excerpt

The endothelins are a family of endothelium-derived peptides that possess characteristically sustained vasoconstrictor properties. Endothelin-1 appears to be the predominant member of the family generated by vascular endothelial cells. In addition to its direct vascular effects, endothelin-1 has inotropic and mitogenic properties, influences homeostasis of salt and water, alters central and peripheral sympathetic...

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PMID: 9794709
DOI: 10.1097/00004872-199816080-00001

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