Article
Manganese-dependent regulation of the endocarditis-associated virulence factor EfaA of Enterococcus faecalis
23 Jan 2003
Abstract excerpt
There is increasing recognition of the emerging role of manganese regulation and acquisition in some pathogenic bacteria. Expression of the Enterococcus faecalis endocarditis-associated virulence factor EfaA is induced by growth in serum. It is demonstrated here that expression of the efaCBA operon encoding a putative ABC-type transporter is regulated by Mn(2+). Transcription of efaCBA and EfaA production were...
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