Article
Circadian variations of transferrin saturation levels in iron-overloaded patients: implications for the screening of C282Y-linked haemochromatosis.
British journal of haematology - 1 Jan 2003
Guillygomarc'h Anne, Christian Jacquelinet, Romain Moirand, Vincent Quentin, Véronique David, Deugnier Yves
Abstract excerpt
The phenotypic screening for genetic haemochromatosis (GH) relies upon the determination of transferrin saturation (TS). In large-scale screening programs, the time of blood sampling can be uneasy to control. We studied the circadian variations of TS at 08.00 hours, 12.00 hours, 18.00 hours and 00.00 hours in 46 C282Y homozygous patients (GH) and 47 non-GH patients (NH), to determine whether the time of blood...
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