Article
Automated measurement of unsaturated iron binding capacity is an effective screening strategy for C282Y homozygous haemochromatosis.
Gut - 1 Mar 2000
Hickman P E, Hourigan L F, Powell L W, Cordingley F, Dimeski G, Ormiston B, Shaw J, Ferguson W, Johnson M, Ascough J, McDonell K, Pink A, Crawford D H
Abstract excerpt
BACKGROUND: C282Y hereditary haemochromatosis is an appropriate condition for population screening. Transferrin saturation, the best screening test to date, is relatively expensive, labour intensive, and cannot be automated. Unsaturated iron binding capacity is a surrogate marker of transferrin saturation and its measurement can be automated. AIMS: To evaluate a screening strategy for C282Y hereditary...
Topics
- Adult
- Aged
- Aged, 80 and over
- Cost-Benefit Analysis
- Evaluation Studies as Topic
- Female
- Genetic Markers
- Genetic Testing
- Genotype
- Hemochromatosis
- Humans
- Iron
- Male
- Middle Aged