Article
Detection of unpaired DNA at meiosis results in RNA-mediated silencing.
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Feb 2003
Hynes Michael J, Todd Richard B
Abstract excerpt
During meiosis, homologous chromosomes must pair in order to permit recombination and correct chromosome segregation to occur. Two recent papers show that meiotic pairing is also important for correct gene expression during meiosis. They describe data for the filamentous fungus Neurospora crassa that show that a lack of pairing generated by ectopic integration of genes can result in silencing of genes expressed...
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