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Article

Combined microsatellite and FGFR3 mutation analysis enables a highly sensitive detection of urothelial cell carcinoma in voided urine.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jan 2003

van Rhijn Bas W G, Lurkin Irene, Chopin Dominique K, Kirkels Wim J, Thiery Jean-Paul, van der Kwast Theo H, Radvanyi François, Zwarthoff Ellen C

Abstract excerpt

PURPOSE: Fibroblast growth factor receptor 3 (FGFR3) mutations were reported recently at a high frequency in low-grade urothelial cell carcinoma (UCC). We investigated the feasibility of combining microsatellite analysis (MA) and the FGFR3 status for the detection of UCC in voided urine. EXPERIMENTAL DESIGN: In a prospective setting, 59 UCC tissues and matched urine samples were obtained, and subjected to MA (23...

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Identifiers

PMID: 12538478

Genes

FGFR3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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