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Androgen insensitivity and male infertility<sup>1</sup>

10 Jan 2003

Abstract excerpt

Abnormal human spermatogenesis can be caused by defects in androgen action because of androgen insensitivity. A variety of mutations have been described in the human androgen receptor gene associated with male infertility. These can be attributed to two molecular mechanisms. First, point mutations in the androgen receptor gene cause alterations in the amino acid sequence and, hence, lead to apparently slight...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 12534933
DOI: 10.1046/j.1365-2605.2003.00369.x

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