Article
Androgen receptor roles in spermatogenesis and infertility.
Best practice & research. Clinical endocrinology & metabolism - 1 Aug 2015
O'Hara Laura, Smith Lee B
Abstract excerpt
Androgens such as testosterone are steroid hormones essential for normal male reproductive development and function. Mutations of androgen receptors (AR) are often found in patients with disorders of male reproductive development, and milder mutations may be responsible for some cases of male infertility. Androgens exert their action through AR and its signalling in the testis is essential for spermatogenesis. AR...
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