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Article

The L1 cell adhesion molecule is essential for topographic mapping of retinal axons.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Jan 2003

Demyanenko Galina P, Maness Patricia F

Abstract excerpt

The retinocollicular projection is a preferred axon guidance pathway for investigating molecular mechanisms of synaptic targeting in the mammalian CNS. Here we identify a previously unrecognized role of the L1 cell adhesion molecule in topographic mapping of retinal ganglion cell (RGC) axons to their targets in the mouse superior colliculus (SC). L1 was transiently expressed on RGC axons during axon growth and...

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Identifiers

PMID: 12533613
PMCID: PMC6741870

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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