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Article

Gravitational unloading effects on muscle fiber size, phenotype and myonuclear number.

Advances in space research : the official journal of the Committee on Space Research (COSPAR) - 1 Jan 2002

Ohira Y, Yoshinaga T, Nomura T, Kawano F, Ishihara A, Nonaka I, Roy R R, Edgerton V R

Abstract excerpt

The effects of gravitational unloading with or without intact neural activity and/or tension development on myosin heavy chain (MHC) composition, cross-sectional area (CSA), number of myonuclei, and myonuclear domain (cytoplasmic volume per myonucleus ratio) in single fibers of both slow and fast muscles of rat hindlimbs are reviewed briefly. The atrophic response to unloading is generally graded as follows: slow...

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Identifiers

PMID: 12530363
DOI: 10.1016/s0273-1177(02)00395-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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