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Article

[Genetic polymorphism of steroid 17 alpha-hydroxylase/17,20-lyase (CYP17) and hyperinsulinemia in endometrial carcinoma].

Voprosy onkologii - 1 Jan 2002

Berstein L M, Imianitov E N, Gamaiunova V B, Kovalevskiĭ A Iu, Kuligina E Sh, Belogubova E V, Buslov K G, Karpova M B, Togo A V, Volkov O N, Kovalenko I G, Chernobrovkina A E

Abstract excerpt

Initiation and/or promotion of endometrial carcinoma is considered to be associated with estrogens and androgens (androstendione) excess as well as hyperinsulinemia and resistance to insulin. It is possible that certain polymorphisms of the genes involved in steroidogenesis or steroid metabolism contribute to carcinoma susceptibility. In the current study, we compared the role of CYP17 biallelic MspA1)...

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PMID: 12530262

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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