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Article

Yeast glycogen synthase kinase-3 activates Msn2p-dependent transcription of stress responsive genes.

Molecular biology of the cell - 1 Jan 2003

Hirata Yuzoh, Andoh Tomoko, Asahara Toshimasa, Kikuchi Akira

Abstract excerpt

The yeast Saccharomyces cerevisiae has four genes, MCK1, MDS1 (RIM11), MRK1, and YOL128c, that encode homologues of mammalian glycogen synthase kinase 3 (GSK-3). A gsk-3 null mutant in which these four genes are disrupted showed growth defects on galactose medium. We isolated several multicopy suppressors of this growth defect. Two of them encoded Msn2p and phosphoglucomutase (PGM). Msn2p is a transcription...

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Share to Gene Expression Regulation, Fungal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Osmotic Pressure

Share to Saccharomyces cerevisiae Proteins

Share to Suppression, Genetic

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Source

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Identifiers

PMID: 12529445
DOI: 10.1091/mbc.e02-05-0247
PMCID: PMC140246

Genes

DDR2
PGM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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