Article
Neisseria gonorrhoeae acquires mutations in analogous regions of gyrA and parC in fluoroquinolone-resistant isolates.
Molecular microbiology - 1 Oct 1994
Belland R J, Morrison S G, Ison C, Huang W M
Abstract excerpt
Neisseria gonorrhoeae homologues of gyrA and parC have been identified using hybridization probes generated from conserved regions of diverse gyrA genes. These genes have been tentatively identified as gyrA and parC, based on predicted amino acid sequence homologies to known GyrA homologues from...
Topics
- Amino Acid Sequence
- Chromosome Mapping
- Chromosomes, Bacterial
- Ciprofloxacin
- DNA Gyrase
- DNA Topoisomerase IV
- DNA Topoisomerases, Type I
- DNA Topoisomerases, Type II
- Drug Resistance, Microbial
- Escherichia coli
- Genes, Bacterial
- Molecular Sequence Data
- Mutation
- Neisseria gonorrhoeae
- Sequence Alignment
- Transformation, Bacterial