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Article

Neisseria gonorrhoeae acquires mutations in analogous regions of gyrA and parC in fluoroquinolone-resistant isolates.

Molecular microbiology - 1 Oct 1994

Belland R J, Morrison S G, Ison C, Huang W M

Abstract excerpt

Neisseria gonorrhoeae homologues of gyrA and parC have been identified using hybridization probes generated from conserved regions of diverse gyrA genes. These genes have been tentatively identified as gyrA and parC, based on predicted amino acid sequence homologies to known GyrA homologues from numerous bacterial species and to ParC from Escherichia coli and Salmonella typhimurium. The gyrA gene maps to a...

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PMID: 7830580
DOI: 10.1111/j.1365-2958.1994.tb01297.x

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