Article
Establishment of T cell lines to bovine beta-casein and beta-casein-derived epitopes in patients with type 1 diabetes.
The Journal of endocrinology - 1 Jan 2003
Monetini L, Barone F, Stefanini L, Petrone A, Walk T, Jung G, Thorpe R, Pozzilli P, Cavallo M G
Abstract excerpt
Enhanced cellular immune response to bovine beta-casein has been reported in patients with type 1 diabetes. In this study we aimed to establish beta-casein-specific T cell lines from newly diagnosed type 1 diabetic patients and to characterise these cell lines in terms of phenotype and epitope specificity. Furthermore, since sequence homologies exist between beta-casein and putative beta-cell autoantigens,...
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