Article
The emerging role of leptin in humans.
Pediatric endocrinology reviews : PER - 1 Mar 2006
Kelesidis Theodore, Mantzoros Christos S
Abstract excerpt
Leptin is an adipocyte-secreted hormone which plays a key role in energy homeostasis. Recent advances in leptin physiology have revealed that the main role of this hormone in humans is to signal energy availability in energy-deficient states. Interventional studies in leptin deficient children and observational studies in normal girls and boys support a role for leptin as a permissive factor for the initiation of...
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