Article
Global regulation of Staphylococcus aureus genes by Rot.
Journal of bacteriology - 1 Jan 2003
Saïd-Salim B, Dunman P M, McAleese F M, Macapagal D, Murphy E, McNamara P J, Arvidson S, Foster T J, Projan S J, Kreiswirth B N
Abstract excerpt
Staphylococcus aureus produces a wide array of cell surface and extracellular proteins involved in virulence. Expression of these virulence factors is tightly controlled by numerous regulatory loci, including agr, sar, sigB, sae, and arl, as well as by a number of proteins with homology to SarA. Rot (repressor of toxins), a SarA homologue, was previously identified in a library of transposon-induced mutants...
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