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Gene and haplotype frequencies for the loci hLA-A, hLA-B, and hLA-DR based on over 13,000 german blood donors.

Human immunology - 1 Jan 2003

Müller Carlheinz R, Ehninger Gerhard, Goldmann Shraga F

Abstract excerpt

Numerous applications in clinical medicine and forensic sciences depend on reliable data concerning the frequencies of human leukocyte antigen (HLA) genes and haplotypes. Assuming a Hardy-Weinberg equilibrium of the underlying population, these frequencies can be estimated from phenotype data using an expectation-maximization-algorithm also known under the name "gene counting." We have refined this algorithm in...

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PMID: 12507825
DOI: 10.1016/s0198-8859(02)00706-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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