Article
[Immunogenetics of optic neuritis in children with multiple sclerosis].
Vestnik oftalmologii - 1 Jan 2000
Guseva M R, Boĭko S Iu, Sudomoina M A, Favorova O O, Boĭko A N, Sidorenko E I, Gusev E I
Abstract excerpt
The aim of the work was to study immunogenetic peculiarities of optic neuritis in children with MS. Using PCR-SSP technique genomic typing was performed on HLA DRB1 gene (chromosome 6p21) of 56 unrelated children with ON registered at least once in clinically verified MS. 264 adult MS patients and 328 healthy controls from the same stratum of population were also genotyped. A very strong correlation of MS with...
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