Article
Polymorphisms of the vascular endothelial growth factor and susceptibility to diabetic microvascular complications in patients with type 1 diabetes mellitus.
Journal of diabetes and its complications - 1 Jan 2000
Yang Bingmei, Cross Deborah F, Ollerenshaw Martin, Millward Beverly A, Demaine Andrew G
Abstract excerpt
There is increasing evidence implicating genetic factors in the susceptibility to diabetic microvascular complications. Recent studies suggest that increased expression of the cytokine vascular endothelial growth factor (VEGF) may play a role in the pathogenesis of diabetic complications. A number of polymorphisms in the promoter region of the VEGF gene have been identified. The aim was to investigate whether an...
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