Article
Captopril enhances transforming growth factor (TGF)-beta1 expression in peripheral blood mononuclear cells: a mechanism independent from angiotensin converting enzyme inhibition? A study in cyclosporine-treated kidney-transplanted patients.
Transplantation - 27 Dec 2002
Di Paolo Salvatore, Schena Antonio, Stallone Giovanni, Grandaliano Giuseppe, Soccio Michela, Cerullo Giuseppina, Gesualdo Loreto, Paolo Schena Francesco
Abstract excerpt
BACKGROUND: Angiotensin (Ang) II blockade has been shown to prevent the development of renal injury in immunologically mediated diseases, but the mechanism whereby it exerts its protective effect has not been clearly defined. Transforming growth factor (TGF)-beta1 is a multifunctional cytokine wi...
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