Article
Variations in immune response genes and their associations with multifactorial immune disorders.
Immunological reviews - 1 Dec 2002
Tsuchiya Naoyuki, Ohashi Jun, Tokunaga Katsushi
Abstract excerpt
There are three genetic methods often used for detecting genes contributing to susceptibility or resistance to multifactorial diseases: nonparametric linkage analysis, case-control association analysis, and transmission disequilibrium test. In this review, we present the theoretical basis that the case-control association study has the highest power of detecting disease genes if there is no population...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
