Article
Molecular and pharmacological diversity of the kinin B1 receptor.
International immunopharmacology - 1 Dec 2002
Hess J Fred, Hey Patricia J, Chen Tsing-Bau, Pettibone Douglas J, Chang Ray S L
Abstract excerpt
The pharmacological properties of the kinin B1 receptor in binding the endogenous kinin peptides are known to differ across species. Molecular cloning has revealed that these pharmacological differences arise from the diversity within the BDKRB gene. In this report, the molecular diversity of the human BDKRB1 gene is expanded by the identification of eight single nucleotide polymorphisms (SNPs) in the coding...
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