Article
Expression profiling identifies 147 genes contributing to a unique primate neointimal smooth muscle cell phenotype.
Arteriosclerosis, thrombosis, and vascular biology - 1 Dec 2002
Geary Randolph L, Wong James M, Rossini Anthony, Schwartz Stephen M, Adams Lawrence D
Abstract excerpt
OBJECTIVE: This study represents the first in an effort to systematically characterize different intimas by using expression array analysis. METHODS AND RESULTS: We compared smooth muscle cells (SMCs) of the neointima formed 4 weeks after aortic grafting with those from normal aorta and vena cava from cynomolgus monkeys. Hybridization to cDNA arrays identified subsets of 147 and 45 genes differentially expressed...
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