Article
The protein kinase Kic1 affects 1,6-beta-glucan levels in the cell wall of Saccharomyces cerevisiae.
Microbiology (Reading, England) - 1 Dec 2002
Vink Edwin, Vossen Jack H, Ram Arthur F J, van den Ende Herman, Brekelmans Stephan, de Nobel Hans, Klis Frans M
Abstract excerpt
KIC1 encodes a PAK kinase that is involved in morphogenesis and cell integrity. Both over- and underexpressing conditions of KIC1 affected cell wall composition. Kic1-deficient cells were hypersensitive to the cell wall perturbing agent calcofluor white and had less 1,6-beta-glucan. When Kic1-deficient cells were crossed with various kre mutants, which also have less 1,6-beta-glucan in their wall, the double...
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