Article
Mutation of TRS130, which encodes a component of the TRAPP II complex, activates transcription of OCH1 in Saccharomyces cerevisiae.
Current genetics - 1 Nov 2002
Yamamoto Katsuyoshi, Jigami Yoshifumi
Abstract excerpt
The Saccharomyces cerevisiae Och1p is required for the initiation of the mannose outer chain elongation of cell wall mannoproteins. A trs130(ts1) mutant that showed an elevated expression of the OCH1-reporters was isolated in our laboratory. In this study, we attempted to gain an understanding of the relationship between the defect in the Trs130p function and the elevated expression of OCH1. The trs130(ts1)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
