Experimental Modulation of Cell-Cell Adhesion, Invasiveness and Differentiation in Trophoblast Cells

Abstract excerpt

The establishment of pregnancy in the human decisively depends on the competence of the early trophoblast to interact during implantation with (1). the uterine epithelium and subsequently (2). with the endometrial stroma and blood vessels. In the interaction with uterine epithelium cell-to-cell adhesion appears to be a critical element, involving initially (and astonishingly) apical cell poles of both epithelia....

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