Article

PPARγ/RXRα Heterodimers Control Human Trophoblast Invasion

2001-10-01

Abstract excerpt

The ligand-dependent nuclear receptors PPARγ and RXRα/β were recently determined to be essential for murine placental development and trophoblast differentiation. In the current study we examined the expression and role of the PPARγ/RXRα heterodimers in human invasive trophoblasts. We first report that in human first trimester placenta, PPARγ and RXRα are highly expressed in cytotrophoblasts at the feto-maternal i...

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Literature Corpus work: 140f0fa8-2ec5-509e-b5e1-5e723a63bebf
DOI: 10.1210/jcem.86.10.7924

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