Article
Selective protein exit from yeast endoplasmic reticulum in absence of functional COPII coat component Sec13p.
Molecular biology of the cell - 1 Dec 2002
Fatal Netta, Suntio Taina, Makarow Marja
Abstract excerpt
Sec13p has been thought to be an essential component of the COPII coat, required for exit of proteins from the yeast endoplasmic reticulum (ER). We show herein that normal function of Sec13p was not required for ER exit of the Hsp150 glycoprotein. Hsp150 was secreted to the medium under restrictive conditions in a sec13-1 mutant. The COPII components Sec23p and Sec31p and the GTP/GDP exchange factor Sec12p were...
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