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Article

Taming the mucosal immune response in Crohn's disease.

Best practice & research. Clinical gastroenterology - 1 Dec 2002

van Deventer S J H

Abstract excerpt

New effective therapeutic strategies for inflammatory bowel disease are based on recent knowledge of the regulation of the immune response. Specific defects of innate immunity, such as the NOD2 mutation in a subset of patients with Crohn's disease, have been associated with inflammatory bowel disease and provide new therapeutic targets. The ultimate therapeutic goal is the complete restoration of the mucosal...

Read the complete abstract on PubMed

Topics

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Share to Crohn Disease
Share to Immune Tolerance
Share to Immunity, Mucosal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Intracellular Signaling Peptides and Proteins

Share to Carrier Proteins

Share to Nod2 Signaling Adaptor Protein

Source

Identifiers

PMID: 12473306
DOI: 10.1053/bega.2002.0355

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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