Article
Reduced delayed-rectifier K+ current in the learning mutant rutabaga.
Learning & memory (Cold Spring Harbor, N.Y.) - 1 Jan 2000
Alshuaib Waleed B, Mathew Mini V
Abstract excerpt
In the Drosophila mutant rutabaga, short-term memory is deficient and intracellular cyclic adenosine monophosphate (cAMP) concentration is reduced. We characterized the delayed-rectifier potassium current (IK(DR)) in rutabaga as compared with the wild-type. The conventional whole-cell patch-clamp technique was applied to cultured Drosophila neurons derived from embryonic neuroblasts. IK(DR) was smaller in...
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