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Article

Effect of interactions between amino acid residues 43 and 61 on thermal stability of bacterial formate dehydrogenases.

Biochemistry. Biokhimiia - 1 Oct 2002

Fedorchuk V V, Galkin A G, Yasny I E, Kulakova L B, Rojkova A M, Filippova A A, Tishkov V I

Abstract excerpt

NAD+-dependent formate dehydrogenases (EC 1.2.1.2, FDH) of methylotrophic bacteria Pseudomonas sp. 101 (PseFDH) and Mycobacterium vaccae N10 (MycFDH) exhibit high homology. They differ in two amino acid residues only among a total of 400, i.e., Ile35 and Glu61 in MycFDH substitute for Thr35 and Lys61 as in PseFDH. However, the rate constant for MycFDH thermal inactivation in the temperature range of 54-65 degrees...

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PMID: 12460112
DOI: 10.1023/a:1020915324159

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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