Article
Genetics and Biology of Pancreatic Ductal Adenocarcinoma.
Hematology/oncology clinics of North America - 1 Aug 2015
Dunne Richard F, Hezel Aram F
Abstract excerpt
Pancreatic ductal adenocarcinoma remains a clinical challenge. Thus far, enlightenment on the downstream activities of Kras, the tumor's unique metabolic needs, and how the stroma and immune system affect it have remained untranslated to the clinical practice. Given the numbers of diverse therapies in development and a growing knowledge about how to evaluate these systems preclinically and clinically, this is...
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