Article
Two copies of mthmg1, encoding a novel mitochondrial HMG-like protein, delay accumulation of mitochondrial DNA deletions in Podospora anserina.
Eukaryotic cell - 1 Aug 2002
Dequard-Chablat Michelle, Allandt Cynthia
Abstract excerpt
In the filamentous fungus Podospora anserina, two degenerative processes which result in growth arrest are associated with mitochondrial genome (mitochondrial DNA [mtDNA]) instability. Senescence is correlated with mtDNA rearrangements and amplification of specific regions (senDNAs). Premature death syndrome is characterized by the accumulation of specific mtDNA deletions. This accumulation is due to indirect...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
